Example of dopamine excess. It can the regulation of dopamine is very important. For muscle control. And its regulation changes during long-term runn. likely to the runners we feel. As for how the release of dobaan is regulat .There seems to be much room for scientific discussion and clarification. Photo credit: sports horizons johannes fuss publish a very interesting study in 2015. They found cannabinoid receptor 1 (cb1) is the main regulator of runner’s. high transgenic mice and behavioral analysis. And this discovery could explain .Why dopamine alone is not enough to make a runner high.
During running, the body releases dopamine and
Endocannabinoid (ecb) into Namibia Phone Number the bloodstream. At this time, endorphins are responsible for blocking pain signals, while endocannabinoids bind to cannabinoid receptor 1 on gabaergic neurons to block the downstream inhibition of dopamine-secreting neurons. Inhibit signaling, which makes dopamine-secreting neurons more likely to activate and produce dopamine. In the experiment, they divided the mice into a running group and a non-running group. Five hours before the behavioral test. The mice in the runn to run freely on the rollers .And immediately .The rollers retract.The mice were given a light-dark anxiety behavioral test. Under normal circumstances. Mice like to stay in a dark place makes them feel more secure. So this experiment can use the time mice spend. Exploring in a bright place as an indicator of anxiety.
The longer the time in the bright place
The lower the anxiety value. They found that mice in the running group spent significantly longer in the light than the non-running control group, and mice in the running group were also significantly less sensitive to pain on subsequent pain tests. The behavioral test. The mice in all groups immediately open to run the roller for one hour. It was found that the total distance run by the mice in the running group after the test was significantly lower than that in the control group that did not run before. The mice in the group were relatively calmer than the mice in the control group after the test. From their animal experiments, they can see that the mice experience psychological changes similar to runners after running for a long time, but “Happy mood” cannot be measured, because it is very subjective compared to other pleasure-oriented emotions, so it is impossible to measure it. It is clearly defined in animal experiments.